Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergy: People who are allergic to sulfa medications may also be allergic to chlorpropamide.
Blood sugar control: For people with diabetes, loss of blood sugar control may occur during illness or stressful situations such as trauma or surgery. Under these conditions, your doctor may recommend or prescribe insulin until the situation improves.
Diabetes complications: Chlorpropamide has not been proven to prevent the development of complications associated with diabetes.
Hemolytic anemia: People with a genetic deficiency of glucose-6-phosphate dehydrogenase (G6PD) should not take this medication as it may cause hemolytic anemia (a rapid destruction of red blood cells).
Low blood sugar: This medication can cause low blood sugar (hypoglycemia). This is more likely to occur for people with reduced kidney or liver function or who are malnourished, not eating enough, exercising vigorously, or have reduced adrenal gland function. Symptoms of low blood sugar include:
- lack of energy
- numbness or tingling
People taking this medication should monitor their blood sugar regularly and keep emergency glucose available to treat low blood sugar levels. Contact your doctor if you experience low blood sugar while taking this medication.
Reduced response: Over a period of time, people may become less responsive to medications such as chlorpropamide because of worsening of their diabetes. If your blood sugar levels are not controlled while taking this medication, contact your doctor.
Pregnancy: Chlorpropamide should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: Chlorpropamide passes into breast milk and is not recommended for women who are breast-feeding.
Children: The safety and effectiveness of using this medication for children have not been established.