Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Fluid and electrolyte balance: Fluid intake should be adjusted in order to reduce the possibility of water retention and low levels of sodium in the blood, especially for very young people and for seniors. People who are dehydrated should wait until their water balance has been adequately restored before taking desmopressin. Seniors should be closely observed for possible water retention and low sodium in the blood due to excessive fluid intake. Talk to your doctor about adjusting the amount of fluid intake that is right for you. For control of nighttime urination, a restricted fluid intake is recommended a few hours before using this medication.
Medical conditions: Desmopressin is not effective in controlling excessive urination caused by kidney disease, diabetes, psychosomatic conditions, low blood potassium, or high blood calcium. People with severe bladder or voiding problems, and those with cystic fibrosis, should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Tolerance: There are reports of changes in response over time, usually when the medication has been used for periods longer than 6 months. Some people may experience decreased responsiveness, while others may experience a shortened duration of effect.
Pregnancy: This medication has been used during pregnancy with no harm reported. However, no controlled studies have been done on its use by pregnant women. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if desmopressin from desmopressin tablets passes into breast milk. If you are a breast-feeding mother and are taking desmopressin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.