To treat hypercalcemia (high blood calcium) for people who have cancer, clodronate is started with an intravenous infusion (injection into the vein), and then switched to oral (by mouth) maintenance treatment.
The recommended adult dose of the intravenous infusion is 300 mg daily. Following intravenous treatment, oral treatment is started at a recommended dose of 1,600 mg to 2,400 mg daily given as a single daily dose or as 2 divided doses. The maximum recommended daily dose is 3,200 mg.
To treat cancer that has spread to bones (bone metastases) due to different types of tumours, the recommended initial dose is 1,600 mg daily given orally (by mouth). If needed, this dose may be increased by your doctor. The maximum daily dose is 3,200 mg.
Clodronate capsules should be taken on an empty stomach with a glass of plain water, at least 2 hours before or after food.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.