Alprostadil is given by injection into the blood-filled spaces of the penis. Your doctor will determine the appropriate dose of alprostadil by assessing the nature of the impotence. Your doctor will give an initial injection and then slowly increase the dose over the course of the next injections until the lowest dose for an effective erection is found. Erection should occur within 5 to 20 minutes after injection.
The initial dose of alprostadil is usually around 1.25 µg to 2.5 µg (depending on the cause of the erectile dysfunction). The amount of medication will be increased until the lowest effective dose is reached. The maximum daily dose should not exceed 60 µg. Alprostadil should be used no more than once a day and no more than 3 times a week, with at least 24 hours between each dose.
If the erection lasts for 2 hours, try to reduce the erection by methods suggested by the doctor. A prolonged erection (3 hours or more) should be reported to the doctor immediately.
Do not inject alprostadil into an erect penis. Never increase or decrease the dose without consulting your doctor. Once the correct dose has been found, the first few injections will take place at your doctor's office so you can learn how to inject the medication properly. Once your doctor is assured that you are comfortable with the procedure, you will be given a prescription for a kit to use at home.
Refer to the package insert for details on how to mix the medication and inject it properly. Everything you need to use the medication comes with the kit. It is important to visit your doctor regularly, at least once every 3 months during treatment, to ensure that the medication is working safely and effectively.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor.
Store unused vials of this medication between 2°C to 30°C and do not let it freeze. Once mixed, the solution must be used immediately. Keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.