Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Ectopic pregnancy: There is an increased chance of ectopic pregnancy (i.e., the baby develops in one of the fallopian tubes instead of in the uterus) in women who conceive following clomiphene therapy. It is important to have an early ultrasound to ensure that the baby is developing inside the uterus.
Following instructions: It is extremely important to understand your treatment and to follow instructions closely. Be sure to ask your doctor any questions you might have.
Multiple births: The incidence of multiple pregnancy (including twins, triplets, quadruplets, and quintuplets) can be up to 10 times greater when conception occurs during a cycle in which clomiphene therapy is taken.
Ovarian cysts: With clomiphene therapy, there is the possibility of ovarian cyst formation. Women should notify their doctor of any abdominal or pelvic pain, weight gain, discomfort, or bloating after taking clomiphene.
Women with ovarian hyperstimulation syndrome (OHSS) may also have difficulty breathing and decreased amounts of urine. Your doctor will conduct regular pelvic examinations between 2 and 3 weeks after starting each course of therapy.
Ovarian enlargement and ovarian hyperstimulation syndrome (OHSS): These conditions may occur with clomiphene therapy. Early warning signs include abdominal or pelvic pain, bloating, nausea, vomiting, diarrhea, and weight gain. Notify your doctor immediately if any of these symptoms occur after taking clomiphene.
Vision changes: Blurring of vision or other sight problems (such as afterimages, spots, flashes, double vision, or sensitivity to light) may occasionally occur while taking clomiphene or shortly after therapy finishes. These types of sight problems may make it more dangerous to drive or operate machinery, particularly under conditions where light varies. If you experience such effects, stop taking the medication and contact your doctor.
Pregnancy: Clomiphene should not be taken during pregnancy.
Breast-feeding: It is not known if clomiphene passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Clomiphene may also reduce the amount of milk produced by breast-feeding mothers. Talk to your doctor about whether you should continue breast-feeding.
Children: This medication is intended for use by women of child-bearing age and therefore, the safety and effectiveness of this medication have not been established for children.
Seniors: This medication is intended for use by women of child-bearing age and therefore, the safety and effectiveness of this medication have not been established for seniors.