Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take this medication.
Chest pain/heart attack: Rarely, this medication may worsen angina (chest pain) or precipitate a heart attack when it is first started or when the dose is increased. People with severe heart disease seem to be more at risk. If you experience worsening chest pain or symptoms of a heart attack (e.g., chest pain, pressure, or heaviness; nausea; shortness of breath; cool, clammy skin; anxiety) while taking this medication, get immediate medical attention.
Grapefruit juice: Grapefruit juice may increase the effects of amlodipine. Avoid grapefruit juice while taking this medication.
Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have liver disease or decreased liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may recommend a lower dose.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if amlodipine passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of amlodipine have not been established for children under 6 years of age.
Seniors may be more sensitive to the side effects of amlodipine. Your doctor may suggest a lower dose.