The recommended adult dose of linaclotide to treat symptoms of irritable bowel syndrome with constipation is 290 µg taken once a day.
The recommended adult dose of linaclotide for chronic constipation is 145 µg taken once daily.
This medication should be taken on an empty stomach, at least 30 minutes before the first meal of the day. Do not crush or chew the capsules. Swallow the capsules whole with some water.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor.
If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, in its original package. Protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.