Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: Allergic reactions, including difficulty breathing or swelling of the throat and mouth, can occur with this medication.
Blood clotting: This medication can reduce the number of platelet cells in the blood. Platelets help the blood to clot, and a shortage could make you bleed more easily. Tell your doctor of any signs that your blood is not clotting as quickly. Such symptoms may include black and tarry stools, blood in the urine, easy bruising, or cuts that won't stop bleeding.
Infection: As well as killing cancer cells, this medication can reduce the number of cells that fight infection in the body (white blood cells). Avoid contact with people who have contagious infections and tell your doctor if you begin to notice signs of an infection, such as fever or chills.
Kidney and liver function: This medication can impair kidney and liver function. Your doctor will monitor you for this with blood tests.
Pregnancy: There are no adequate studies of use of this medication by pregnant women. This medication should not be given during pregnancy. If you become pregnant while receiving this medication, contact your doctor immediately.
Breast-feeding: It is not known if dacarbazine passes into breast milk. If you are a breast-feeding mother and are receiving this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: The safety and effectiveness of using this medication have not been established for seniors.