Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Effectiveness: Desmopressin is not effective in controlling excessive urination caused by kidney disease, psychiatric conditions, low blood potassium, or high blood calcium.
Fluid and electrolyte balance: Fluid intake should be adjusted in order to reduce the possibility of water retention and low levels of sodium in the blood, especially in children and seniors. Talk to your doctor about how much fluid intake is appropriate for you or your child. People who are taking this medication will be monitored closely by their doctor. Stop taking this medication and get medical attention if you have symptoms of low sodium in the blood such as headache, nausea, or vomiting.
People who are dehydrated should wait until their water balance has been adequately restored before taking desmopressin.
Medical conditions: People with cystic fibrosis, heart failure, bleeding disorders, liver problems, or kidney problems should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Nasal problems: People who have nasal conditions such as inflammation of the nose, scarring, or swelling may not completely absorbed the medication. In these circumstances, the desmopressin nasal solution should not be used. Talk to your doctor about alternatives you can use.
Tolerance: There are reports of changes in response to the medication over time, usually when the medication has been used for longer than 6 months. Some people may experience decreased responsiveness, while others may experience a shortened duration of effect. If you notice this, contact your doctor.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor.
Breast-feeding: It is not known if desmopressin nasal solution passes into breast milk. If you are a breast-feeding mother and are taking desmopressin nasal solution, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children younger than 3 months of age.