Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: This medication can cause serious allergic reactions that can be life-threatening. If you experience hives; difficulty breathing; bluish skin; seizures; severe dizziness; or swelling of the face, tongue, mouth, or lips while receiving this medication, get immediate medical attention. In some cases, people who have had an allergic reaction to this medication will get more allergy symptoms after the infusion has stopped. If this occurs, get immediate medical attention.
Infusion-related reactions: Infusion-related reaction caused by this medication can include skin rash, itchy skin, fever, headache, flushing, hives, and high blood pressure. If these occur, you doctor may suggest that the infusion be slowed down or stopped temporarily. Your doctor may also recommend medications such as antihistamines and corticosteroids to reduce or prevent infusion-related reactions.
Lung problems: People with poor lung function or other lung problems may be more likely to experience infusion-related reactions. Infusion-related reactions include headache, rash, itchy skin, red skin, and high blood pressure. Your doctor will monitor you closely if you have lung problems and are receiving this medication.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if idursulfase passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children under 5 years of age.
Seniors: The safety and effectiveness of using this medication have not been established for seniors.