Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergy: It is possible to experience a severe allergic reaction to topical anesthetics. Before you use lidocaine - prilocaine, inform your doctor about any previous adverse reactions you have had to medications, especially medications used to numb the skin. Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Eyes: Avoid applying this medication to the skin near the eyes. If it happens to come into contact with an eye, immediately rinse the eye with water or sodium chloride solution.
Liver function: Lidocaine - prilocaine is broken down by the liver. Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Methemoglobinemia: Methemoglobinemia is a condition where the blood cannot carry enough oxygen through the body because the “wrong” form of hemoglobin, called methemoglobin, is produced. Prilocaine promotes the body’s production of methemoglobin. Usually, only a small amount of prilocaine is absorbed, so the amount of methemoglobin produced is not a problem. When too much prilocaine is in the body, or you have a condition that already causes excess methemoglobin to be produced, the extra production of methemoglobin may be noticed. If you or your child develop greyish or brownish skin colour, or discoloration around the lips or nail beds, remove the medication and seek immediate medical attention.
Overdose: Lidocaine - prilocaine is absorbed into the body. As such, it is possible to receive too much medication. It is important to apply the medication only to the areas that are being treated and to leave it on only for the length of time your doctor has suggested. Applying this medication to a large area of the body may cause a dangerous amount of medication to be absorbed into the body. Contact with the medication remaining on the patch or dressing can also cause this to happen to children.
Symptoms of too much of this medication in the body include confusion, dizziness, seizures, and very slow heart rate, leading to the heart and breathing to stop. If you or your child experience any of these symptoms, seek immediate medical help.
Skin problems: If you have a skin condition, such as allergic dermatitis, you may need to use this medication for a shorter period of time to get the same numbing effect. Let your doctor know if you have any skin conditions.
The skin where you apply this medication will stay numb for several hours. Be careful to avoid accidental injury or exposure to extremely hot or cold temperatures until complete skin sensation returns.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: Lidocaine passes into breast milk. If you are a breast-feeding mother and are taking lidocaine - prilocaine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Children should be closely watched during and after use of this medications, since they are more at risk of serious side effects. The use of this medication for children older than 3 months and weighing less than 20 kg should be limited to the smallest possible amount for the shortest time that it is effective. Avoid using lidocaine - prilocaine for children less than 3 months of age.