Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Anemia: As with other nonsteroidal anti-inflammatory drugs (NSAIDs), etodolac can make anemia worse. If you have a history of anemia, your doctor may recommend regular blood tests to determine your hemoglobin levels.
Bleeding: NSAIDs such as etodolac can affect how blood clots. Be sure to tell your doctor, dentist, or surgeon that you are taking this medication. You may be asked to stop taking this medication before surgery or dental procedures.
Drowsiness/reduced alertness: Drowsiness, dizziness, and lightheadedness have been reported by some people taking this medication. Do not drive vehicles or undertake other potentially hazardous activities until you have determined that this medication does not affect you in this way.
Fluid retention: As with many other NSAIDs, people have reported increased fluid retention while taking this medication. People who have heart failure, high blood pressure, kidney disease, who are recovering from surgical operations under general anesthesia, or have any other condition that might lead to fluid retention should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney damage: Some people taking this medication may develop kidney damage. If you are taking the medication for a long period of time, your doctor may recommend kidney function tests. People with reduced kidney function, heart failure, and who are taking diuretics (e.g., hydrochlorothiazide, furosemide, indapamide) should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver damage: Some people taking NSAIDs such as etodolac have developed liver damage. Stop taking the medication and contact your doctor as soon as possible if you notice signs of liver damage, such as yellow eyes or skin, abdominal pain, itchy skin, pale stools, or dark urine. Your doctor may recommend regular liver function tests if you are taking this medication for a long period of time.
Potassium: NSAIDs such as etodolac can increase blood levels of potassium. You doctor will check your blood potassium levels while you are taking this medication. People with diabetes, kidney failure, or who are seniors, or are taking certain medications (e.g., ramipril, amiloride) should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Ulcers: NSAIDs such as etodolac may increase the risk of ulcers in the stomach and intestines. If you have had an ulcer, are at risk of experiencing an ulcer (e.g., are senior or smoke), or have medical conditions that make you prone to irritation of the stomach and intestines (e.g., diverticulitis, ulcerative colitis, Crohn's disease), you should talk to your doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring or treatment is needed.
Stop taking the medication and seek immediate medical attention if you develop symptoms of a bleeding ulcer, such as dark tarry stools, blood in the stools, or vomiting up of blood or material that looks like coffee grounds.
Vision changes: Etodolac and other NSAIDs may cause blurred or reduced vision. Stop taking this medication if you experience changes in vision and contact your doctor to have an eye examination arranged.
Pregnancy: The safety of using this medication during pregnancy has not been established. Using this medication during pregnancy is not recommended. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if etodolac passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors who take this medication should be closely monitored by their doctors. Seniors may be more likely to develop side effects and may require a lower dose.