Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: In rare cases, some people may develop an allergic reaction to this medication. Signs of an allergic reaction include a severe rash, swollen face, or difficulty breathing. If these occur, contact your doctor immediately.
Combination treatment: In some situations, this medication may be used in combination with another type of cholesterol-lowering medication called a "statin" (e.g., atorvastatin, pravastatin). If this combination is used, your liver function should be monitored by your doctor. This combination should not be used by pregnant women or people with active liver disease or unexplained, persistently abnormal tests of liver function.
Liver damage: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking this medication.
This medication may cause liver damage. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Muscle pain or damage: This medication may cause muscle pain or damage. If you have unexpected muscle pain, weakness, or tenderness, see your doctor right away, especially if these symptoms do not seem to go away.
Pancreatitis (inflammation of the pancreas): This medication may cause the pancreas to become inflamed. This is called pancreatitis. If you have a history of or are at risk for developing pancreatitis, you should be closely monitored by your doctor while taking this medication. If you develop signs of pancreatitis (e.g., upper left abdominal pain, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen), contact your doctor. If you have a history of pancreatitis, gallstones, alcoholism, or high triglycerides, you may be more at risk of experiencing this. If you have sudden stomach or abdominal pains while taking this medication, contact your doctor immediately.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if ezetimibe passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using ezetimibe have not been established for children under 10 years of age. Ezetimibe is not recommended for children less than 10 years of age.