Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Blood components: Small, temporary decreases in red and white blood cell counts have been observed in people using this medication. Your doctor will check for this with blood tests during the first year of treatment.
Combination therapy: The use of fenofibrate and "statin" medications (e.g., atorvastatin, lovastatin, simvastatin) at the same time may increase the risk of muscle-related side effects. Talk to your doctor about the risks and benefits of taking the two types of medications together.
Gallbladder disease: For some people, fenofibrate may cause gallstones. If you experience abdominal or stomach pain, gas, nausea, or bloating (especially after eating high-fat foods), contact your doctor.
Kidney function: People with impaired kidney function may be more at risk of certain side effects when taking fenofibrate. Depending on the degree of kidney function impairment, lower doses of fenofibrate may be needed. This medication is not recommended for use by people undergoing dialysis treatment.
Liver function: Fenofibrate may affect liver function. Your doctor will monitor this with blood tests. People with current or past liver problems may be more at risk for liver function changes while taking this medication.
Skeletal muscle: Treatment with fenofibrate has been associated on rare occasions with muscle pain, usually in people with reduced kidney function. Contact your doctor as soon as possible if you notice unexplained muscle pain, tenderness, or weakness, particularly if you have malaise (a general feeling of illness) or fever.
Pregnancy: Strict birth control methods must be used by women of childbearing age. If you become pregnant despite birth control methods, stop taking fenofibrate and contact your doctor. Women who plan to become pregnant should stop taking fenofibrate several months in advance.
Breast-feeding: It is not known fenofibrate passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors are more likely to have reduced kidney function and may need lower doses of this medication.