Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Diabetes: Both elevation and lowering of blood sugar levels have been reported with imipramine use. People with diabetes or hypoglycemia (low blood sugar) should monitor their blood glucose levels closely while taking this medication.
Dizziness: Use caution (i.e., move slowly) when rising from a sitting or lying position since imipramine can cause sudden temporary low blood pressure resulting in dizziness.
Drowsiness/reduced alertness: Imipramine may impair the mental or physical abilities required for the potentially hazardous tasks such as driving a car or operating machinery. Use appropriate caution until you determine how this medication affects you.
Heart rhythm: Imipramine can cause abnormal heart rhythms, particularly when taken in high doses. Therefore, seniors and those with a history of heart disease should take imipramine with caution.
Medical conditions: If you have a history of seizures, reduced liver function, heart conditions, glaucoma, certain blood disorders, a history of mania or bipolar disorder, or urinary retention, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Suicidal thoughts: Imipramine may increase the risk of suicidal thoughts, especially when starting therapy or dosage adjustment. Seek medical attention at any signs of worsening condition.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: Imipramine passes into breast milk. If you are a breast-feeding mother and are taking imipramine it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors should use this medication with caution, and should not exceed the recommended dose.