Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Abnormal heart rhythms: This medication can increase the risk of a type of abnormal heart rhythm called QT prolongation, particularly if it is taken with other medications that cause the same effect, such as quinidine, thioridazine, chlorpromazine, mefloquine, and many others.
Check with your pharmacist or doctor to ensure that you are not taking another medication that can cause QT prolongation. People with QT prolongation or a history of heart arrhythmias should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Grapefruit juice: Grapefruit juice may interact with spiramycin if it is consumed while being treated with spiramycin and may cause an increase in serious side effects. Avoid grapefruit juice while taking spiramycin.
Liver function: People with reduced liver function or liver disease should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Overgrowth of organisms: During prolonged or repeated treatment with spiramycin, other bacteria or fungi may be allowed to overgrow. If your condition worsens or does not improve in appropriate amount of time, contact your doctor.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking spiramycin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.