The recommended adult dose of sofosbuvir is 400 mg (1 tablet) taken once daily.
It must be taken with another antiviral medication. Your doctor will determine which other antiviral medication is most appropriate for treating you, depending on characteristics of the hepatitis C virus. If these medications must be stopped, sofosbuvir must also be stopped.
Sofosbuvir may be taken for 12 weeks to 24 weeks, depending on the other antiviral medications you are taking and your body's response to the medication.
Sofosbuvir may be taken with or without food.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
If you vomit less than 2 hours after taking a dose, you should take another tablet. If you vomit more than 2 hours after taking your dose, do not take another tablet until your next regularly scheduled dose.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.