Adults: Methimazole is taken 3 times daily, every 8 hours. The recommended starting total dose of methimazole is 15 mg daily for mild hyperthyroidism, 30 mg to 40 mg daily for moderately severe hyperthyroidism, and 60 mg daily for severe hyperthyroidism. The eventual maintenance dose is normally 5 mg to 15 mg daily.
Children: For children, the daily dose is initially 0.4 mg per kilogram of body weight, divided into 3 doses and given every 8 hours. The eventual maintenance dose is usually one-half the initial dose.
Methimazole can be taken with or without food.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor or pharmacist.
It is important to take this medication exactly as prescribed by your doctor. The 3 daily doses should be taken as close to every 8 hours as possible so that blood levels are kept as constant as possible. If you miss a dose of this medication, take it as soon as possible and check with your doctor or pharmacist.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.