Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Dependence: As with other opioid medications (narcotics), this medication may become habit-forming if taken for long periods of time. Misuse of oxycodone - naloxone usually is not a problem when it is used appropriately for pain relief. Withdrawal symptoms (e.g., body aches, diarrhea, nausea, nervousness, restlessness, runny nose, sneezing, goose bumps, shaking, shivering, nausea, stomach cramps, fast heart rate, fever, sweating) may occur if oxycodone - naloxone is stopped suddenly. People who are taking this medication for a long time and no longer require it for pain control should stop the medication gradually as directed by their doctor.
Drowsiness/reduced alertness: People taking oxycodone - naloxone should not drive a car or perform hazardous tasks until they determine that this medication does not impair their ability to perform these tasks safely.
Medical conditions: People with low blood pressure, heart disease, lung problems, head injury, kidney or liver problems, seizures, or mental health disorders should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Proper use of medication: Oxycodone - naloxone must be swallowed whole and is meant to work over a 12-hour period. Do not chew, break, crush, or dissolve the tablet because the entire 12-hour dose will be absorbed quickly into your body. This can cause serious problems such as overdose, which can be fatal.
Pregnancy: This medication should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. It is not recommended for breast-feeding mothers.
Children: The safety and effectiveness of using this medication have not been established for children.