Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take this medication.
HEALTH CANADA ADVISORY
January 23, 2017
Health Canada has issued new restrictions concerning the use of ofloxacin. To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Allergy: Serious allergic reactions have been reported by people who take this medication. These reactions often occur following the first dose. Signs of an allergic reaction include a severe rash, hives, swollen face or throat, or difficulty breathing. If these occur, seek immediate medical attention.
Diabetes: Problems with blood glucose control, including the onset of high or low blood glucose, have been reported with ofloxacin. This usually occurs for people with diabetes who use insulin or take an antidiabetes medication by mouth (e.g., glyburide). If you have diabetes and are taking ofloxacin, carefully monitor your blood glucose.
Diarrhea: People taking this medication may develop diarrhea caused by an infection with the bacteria C. difficile. If you have loose, watery, and bloody bowel movements, with or without fever or stomach cramps, after taking ofloxacin, get medical attention as soon as possible. Diarrhea caused by C. difficile infection can lead to serious health problems if it is not properly treated.
Drowsiness/reduced alertness: Ofloxacin may cause drowsiness or dizziness. Do not drive or engage in other activities requiring alertness if the medication affects you in this way.
Fluids: Drink plenty of fluids while taking this medication. This will help to avoid the possible development of crystals in your urine.
Kidney function: Kidney disease or reduced kidney function may cause this medication to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: If you have reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Neuromuscular disorders: People with myasthenia gravis (an autoimmune disorder that causes muscle weakness) should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Seizures: If you have a history of seizures or have a medical condition known to make seizures more likely, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Sun sensitivity: People who take ofloxacin are more likely to suffer from sunburn. While taking ofloxacin, avoid spending time in the sun and when you do, use a sunscreen with a minimum SPF 15. Stop taking the medication if sun sensitivity occurs.
Tendinitis: Ofloxacin may increase the chance of tendon injury. This occurs more commonly for people who are also taking corticosteroid medications, however it can happen to anyone who takes ofloxacin. If you notice any new pain in the tendons, stop taking ofloxacin, avoid physical exercise, and contact your doctor as soon as possible.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, stop taking it and contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking ofloxacin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children and adolescents: The safety and effectiveness of using this medication have not been established for children. Ofloxacin is not recommended for children and adolescents under 18 years of age.