HEALTH CANADA ADVISORY
February 4, 2014
Health Canada has issued new restrictions concerning the use of eprosartan. To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Dizziness/drowsiness: Eprosartan may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how this medication affects you.
Kidney problems: Eprosartan may affect the function of the kidneys, especially in those who already have kidney problems.
Taking diuretics (water pills) or aliskiren may further increase the risk of kidney problems. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking this medication.
Low blood pressure: Occasionally, a larger-than-expected decrease in blood pressure occurs after taking eprosartan. In some cases, this can happen after the first dose. It is more likely to occur if you also taking diuretics (water pills), have a reduced salt intake, are on dialysis, or are experiencing diarrhea or vomiting.
Blood pressure should be monitored more often in these situations. If you have low blood pressure or are just starting this medication or increasing the dose, you should move slowly from a reclining to an upright position to reduce the risk of dizziness.
Pregnancy: You should not take eprosartan if you are pregnant because it can cause significant harm to an unborn child. If you discover you are pregnant while taking this medication, stop taking it and tell your doctor at once.
Breast-feeding: It is not known if eprosartan passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: It is not known how safe and effective eprosartan is for children.
Seniors: Seniors may be at increased risk of side effects due to reduced kidney or liver function. A lower starting dose may be prescribed by your doctor to reduce this risk.