Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Asthma: Patients with asthma and certain other breathing problems should not being given pindolol.
Cholesterol: Increases in cholesterol and triglyceride levels may occur when taking hydrochlorothiazide.
Diabetes: The signs of low blood sugar may not be as noticeable when taking pindolol. Hydrochlorothiazide may make it more difficult for people with diabetes to control their blood sugar. People with diabetes who take insulin or other medications that work by reducing blood sugar should be cautious and monitor blood sugar carefully while taking this medication. Dose adjustment of antidiabetes medications, including insulin, may be required.
Drowsiness/reduced alertness: Dizziness or fatigue may occur when starting treatment with this medication. This may impair your ability to drive or operate machinery. Exercise caution with these activities until you find out whether the medication affects you in this way.
Fluid and electrolyte balance: Levels of electrolytes such as potassium, sodium, magnesium, and chloride can be reduced by the use of hydrochlorothiazide. Your doctor will periodically check to see if your electrolytes remain in balance. A potassium supplement may be necessary when taking this medication. Warning signs or symptoms of fluid and electrolyte imbalance include dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, seizures, confusion, muscle pains or cramps, muscular fatigue, low blood pressure, racing heartbeat, and nausea and vomiting.
Hyperthyroidism (high level of thyroid hormones): People with hyperthyroidism should be cautious while taking pindolol as it may reduce the symptoms of this condition, giving a false impression of improvement. Stopping the medication suddenly could worsen this condition.
Lupus: Hydrochlorothiazide may worsen the symptoms of this condition.
Severe allergies: People with allergies severe enough to cause anaphylaxis (a severe allergic reaction where swelling of the face, lips, and throat make it difficult to breathe) should talk to their doctor about what to do if they have an allergic reaction. Pindolol may make it more difficult to treat their allergic reaction with epinephrine.
Skin conditions: Various skin rashes and dry eyes have been reported with use of this medication.
Stopping usage: This medication should not be stopped suddenly by people who have angina. There have been reports of severe worsening of angina and of heart attack or abnormal heart rhythms occurring in people with angina who have stopped this medication abruptly.
Surgery: If you are scheduled for surgery, inform all doctors involved in your care that you are taking a medication that contains pindolol.
Pregnancy: Pindolol - hydrochlorothiazide should not be taken by pregnant women. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking pindolol - hydrochlorothiazide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.