Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: Allergic reactions, including difficulty breathing or swelling of the throat and mouth, can occur with this medication. If you experience any of these symptoms, get immediate attention.
Blood clotting: This medication can reduce the number of platelet cells in the blood. Platelets help the blood to clot, and a shortage could make you bleed more easily. Tell your doctor of any signs that your blood is not clotting as quickly as usual. Such symptoms may include black and tarry stools, blood in the urine, easy bruising, or cuts that won't stop bleeding.
Damage to cells: This medication can potentially cause cancer, birth defects, and temporary or permanent fertility problems.
Infection: As well as killing cancer cells, this medication can reduce the number of cells that fight infection in the body (white blood cells). Avoid contact with people who have contagious infections and tell your doctor if you begin to notice signs of an infection, such as fever or chills, or if you have an existing infection before starting treatment with teniposide.
Kidney or liver disease: The side effects of teniposide may be increased in people with kidney or liver disease. People with kidney or liver disease should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: There are no adequate studies of using this medication during pregnancy. Women who could become pregnant should used appropriate birth control methods while receiving this medication. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if teniposide passes into breast milk. Women who are receiving this medication should not breast-feed.
Children: This medication contains benzyl alcohol, which has been shown to cause severe side effects in newborns.