Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Diarrhea: Diarrhea is a very common side effect of this medication. If you experience diarrhea, taking miglustat between meals may help. If the diarrhea is bothersome, contact your doctor.
Dizziness/reduced alertness: Miglustat commonly causes dizziness. Avoid driving or operating machinery until you know how this medication affects you.
Kidney disease: Miglustat is removed from the body by the kidneys and its elimination may be reduced in people with kidney disease. People with kidney disease should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Severe Gaucher disease: The safety and effectiveness of miglustat have not been evaluated for people with severe Gaucher disease. Miglustat is used for mild to moderate type 1 Gaucher disease.
Pregnancy: This medication should not be used by women during pregnancy as it may cause harm to the unborn baby. Both men and women should use a reliable method of contraception. Men should not father a child while they are taking miglustat and for 3 months after stopping the medication. If you become pregnant while you are taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if miglustat passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication for type I Gaucher disease have not been established in children under 18 years of age. The safety and effectiveness of using this medication for Niemann-Pick type C disease have not been established in children under 4 years of age.