Some side effects reported with the use of globe artichoke are diarrhea and flatulence
Globe artichoke may interact with some medications, including antiplatelet medications (e.g., ASA, clopidogrel), anticoagulant medications (e.g., warfarin), or medications to lower cholesterol (e.g., rosuvastatin).
Do not use globe artichoke if you have a biliary obstruction (a blockage in the bile duct). If you have gallstones, check with your health care provider before using globe artichoke.
Do not use globe artichoke if you are allergic to it or to any plants in the Asteraceae family (e.g. chamomile, ragweed, chrysanthemum, sunflower, tansy and yarrow).
Do not use globe artichoke if you are pregnant or breast-feeding.
Contact your health care provider if your symptoms persist or worsen.
Before taking any new medications, including natural health products, speak to your physician, pharmacist, or other health care provider. Tell your health care provider about any natural health products you may be taking.