Melatonin is safe for most adults when taken by mouth for a short term. If you are using melatonin for more than 4 weeks or your symptoms last more than 4 weeks, consult your health care provider. Common side effects reported include nausea, vomiting, headache, daytime sleepiness, dizziness, stomach cramps, and irritability. Do not drive or use machinery for 5 hours after taking melatonin.
It can interact with certain medications, including anticoagulants, diabetes medications, seizure medications, blood pressure medications, sedativesedativean agent that induces sleep, relaxes, and reduces tensions and sleeping pills, psychotropic medications, steroids, and immunosuppressants. It can cause more drowsiness when used with other medications that may also have this side effect (e.g., alcohol, sedatives, benzodiazepines such as lorazepam, temazepam).
Melatonin should not be used by people who are pregnant or breast-feeding.
Before taking melatonin, consult a health care professional if you have a history of asthma, seizures, diabetes, diseases affecting the immune system, high blood pressure, cardiovascular disease, depression, liver or kidney disease, migraines, hypoglycemia, or hormonal disorders.
Before taking any new medications, including natural health products, speak to your physician, pharmacist, or other health care provider. Tell your health care provider about any natural health products you may be taking.